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Glecaprevir and pibrentasvir and Food

Result of checking the interaction of Glecaprevir and pibrentasvir and Food for safety when used together.

Check result:
Glecaprevir and pibrentasvir <> Food
Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Consumer information for this interaction is not currently available.

Professional:

ADJUST DOSING INTERVAL: Food enhances the oral bioavailability of glecaprevir and pibrentasvir. Relative to fasting conditions, mean glecaprevir systemic exposure (AUC) increased by 83% to 163% and mean pibrentasvir AUC increased by 40% to 53% when administered with moderate to high fat meals.

MANAGEMENT: Glecaprevir-pibrentasvir should be administered with food.

References:
  • "Product Information. Mavyret (glecaprevir-pibrentasvir)." Abbott Pharmaceutical, Abbott Park, IL.
Glecaprevir and pibrentasvir

Generic Name: glecaprevir / pibrentasvir

Brand Name: Mavyret

Synonyms: Glecaprevir and Pibrentasvir

What is Glecaprevir and pibrentasvir?
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