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Pomalidomide and Food

Result of checking the interaction of Pomalidomide and Food for safety when used together.

Check result:

Pomalidomide <> Food

Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

If you are a smoker, you should be aware that cigarette smoking may reduce the blood levels and effects of pomalidomide. Talk to your health care professional if you have any questions or concerns. Pomalidomide should be taken with water the same time everyday on an empty stomach, at least 2 hours before or 2 hours after a meal. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Cigarette smoking may reduce pomalidomide exposure due to induction of CYP450 1A2, the isoenzyme that is responsible for the metabolic clearance of pomalidomide along with CYP450 3A4.

MANAGEMENT: Patients should be advised that smoking may reduce the efficacy of pomalidomide therapy. Pomalidomide should be taken on an empty stomach, at least 2 hours before or 2 hours after a meal.

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