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Actoplus Met and High Blood Pressure (Hypertension)

Result of checking the interaction of Actoplus Met and High Blood Pressure (Hypertension) for safety when used together.

Check result:

Actoplus Met <> High Blood Pressure (Hypertension)

Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Thiazolidinediones can cause dose-related edema. Therapy with thiazolidinediones should be administered cautiously in patients at risk for congestive heart failure as well as those with fluid overload or other conditions that may be adversely affected by excess fluid such as hypertension. Patients should be monitored for signs and symptoms of heart failure such as dyspnea, swelling of legs or ankles, and weight gain.

Professional:

References:

"Product Information. Rezulin (troglitazone)." Parke-Davis, Morris Plains, NJ.
"Product Information. Avandia (rosiglitazone)" SmithKline Beecham, Philadelphia, PA.
"Product Information. Actos (pioglitazone)" Takeda Pharmaceuticals America, Lincolnshire, IL.
Thomas ML, Lloyd SJ "Pulmonary edema associated with rosiglitazone and troglitazone." Ann Pharmacother 35 (2001): 123-4

Actoplus Met

Generic Name: metformin / pioglitazone

Brand Name: Actoplus Met, Actoplus Met XR

Synonyms: n.a.

What is Actoplus Met?