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Actoplus Met and Obesity

Result of checking the interaction of Actoplus Met and Obesity for safety when used together.

Check result:

Actoplus Met <> Obesity

Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Thiazolidinediones can cause dose-related weight gain, which may be undesirable in obese patients attempting to lose weight. The mechanism of weight gain is unclear but probably involves a combination of fluid retention and fat accumulation. In postmarketing experience with rosiglitazone, there have been reports of unusually rapid increases in weight, greater than those generally observed in clinical trials. Patients who experience such increases should be assessed for fluid retention and volume-related events such as excessive edema and congestive heart failure.

Professional:

References:

"Product Information. Actos (pioglitazone)" Takeda Pharmaceuticals America, Lincolnshire, IL.
"Product Information. Avandia (rosiglitazone)" SmithKline Beecham, Philadelphia, PA.

Actoplus Met

Generic Name: metformin / pioglitazone

Brand Name: Actoplus Met, Actoplus Met XR

Synonyms: n.a.

What is Actoplus Met?