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Captopril and Hydrochlorothiazide and Food

Result of checking the interaction of Captopril and Hydrochlorothiazide and Food for safety when used together.

Check result:

Captopril and Hydrochlorothiazide <> Food

Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Consumer information for this interaction is not currently available.

Professional:

GENERALLY AVOID: Moderate-to-high dietary intake of potassium can cause hyperkalemia in some patients who are using angiotensin converting enzyme (ACE) inhibitors. In some cases, affected patients were using a potassium-rich salt substitute. ACE inhibitors can promote hyperkalemia through inhibition of the renin-aldosterone-angiotensin (RAA) system.

MANAGEMENT: It is recommended that patients who are taking ACE inhibitors be advised to avoid moderately high or high potassium dietary intake. Particular attention should be paid to the potassium content of salt substitutes.

References:

Ray K, Dorman S, Watson R "Severe hyperkalaemia due to the concomitant use of salt substitutes and ACE inhibitors in hypertension: a potentially life threatening interaction." J Hum Hypertens 13 (1999): 717-20
"Product Information. Vasotec (enalapril)." Merck & Co, Inc, West Point, PA.
Good CB, McDermott L "Diet and serum potassium in patients on ACE inhibitors." JAMA 274 (1995): 538

Captopril and Hydrochlorothiazide

Generic Name: captopril / hydrochlorothiazide

Brand Name: Capozide 25/15, Capozide 25/25, Capozide 50/15, Capozide 50/25

Synonyms: Hydrochlorothiazide and captopril

What is Captopril and Hydrochlorothiazide?