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Didanosine Delayed-Release Enteric-Coated Capsules and High Blood Pressure (Hypertension)

Result of checking the interaction of Didanosine Delayed-Release Enteric-Coated Capsules and High Blood Pressure (Hypertension) for safety when used together.

Check result:

Didanosine Delayed-Release Enteric-Coated Capsules <> High Blood Pressure (Hypertension)

Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Didanosine (ddI) formulations have a high sodium content. There are 265 mg of sodium per tablet and 1380 mg per packet of powder for oral solution, which may be of concern in patients with conditions that may be adversely affected by excessive amounts of sodium, such as congestive heart failure, hypertension, and fluid retention. Each tablet also contains 8.6 mEq of magnesium. Patients with significant renal impairment may not tolerate these loads.

Professional:

References:

Schindzielorz A, Pike I, Daniels M, Pacelli L, Smaldone L "Rates and risk factors for adverse events associated with didanosine in the expanded access program." Clin Infect Dis 19 (1994): 1076-83
Pike IM, Nicaise C "The didanosine Expanded Access Program: safety analysis." Clin Infect Dis 16 (1993): S63-8
Willocks L, Brettle R, Keen J "Formulation of didanosine (ddI) and salt overload." Lancet 339 (1992): 190

Didanosine Delayed-Release Enteric-Coated Capsules

Generic Name: didanosine

Brand Name: Videx, Videx EC

Synonyms: Didanosine

What is Didanosine Delayed-Release Enteric-Coated Capsules?