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Leader Heartburn Relief and Caffeine

Result of checking the interaction of Leader Heartburn Relief and Caffeine for safety when used together.

Check result:

Leader Heartburn Relief <> Caffeine

Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Caffeine effects may be increased in patients also taking cimetidine. The mechanism may be due to decreased caffeine metabolism induced by cimetidine. Although adequate clinical data are lacking, a reduction in dose or elimination of caffeine may be needed if excess CNS stimulation is observed.

References:

Broughton LJ, Rodgers HJ "Decreased systenuc clearance of caffeine due to cimetidine." Br J Clin Pharmacol 12 (1981): 155-9
"Product Information. Tagamet (cimetidine)." SmithKline Beecham, Philadelphia, PA.

Leader Heartburn Relief

Generic Name: cimetidine

Brand Name: Tagamet HB, Tagamet

Synonyms: n.a.

What is Leader Heartburn Relief?