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Miconazole oral buccal and High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)

Result of checking the interaction of Miconazole oral buccal and High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia) for safety when used together.

Check result:
Miconazole oral buccal <> High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)
Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Elevations in cholesterol and triglyceride levels may occur in patients receiving intravenous miconazole and are attributed to the drug vehicle, Cremophor EL (polyethoxylated castor oil). These increases are reversible upon discontinuation of miconazole therapy. Clinicians should be cognizant of these effects when interpreting lab results of hyperlipidemic patients during treatment with miconazole.

Professional:

Elevations in cholesterol and triglyceride levels may occur in patients receiving intravenous miconazole and are attributed to the drug vehicle, Cremophor EL (polyethoxylated castor oil). These increases are reversible upon discontinuation of miconazole therapy. Clinicians should be cognizant of these effects when interpreting lab results of hyperlipidemic patients during treatment with miconazole.

References:
  • Rose HD, Roth DA, Barboriak JJ "Hyperlipidemia related to miconazole therapy." Ann Intern Med 91 (1979): 491-2
  • Heel RC, Brogden RN, Pakes GE, Speight TM, Avery GS "Miconazole: a preliminary review of its therapeutic efficacy in systemic fungal infections." Drugs 19 (1980): 7-30
  • Wade TR, Jones HE, Chanda JJ "Intravenous miconazole therapy of mycotic infections." Arch Intern Med 139 (1979): 784-6
  • Naito HK, McHenry MC, Lewis LA "Drug-induced dyslipoproteinemia: a report of two cases." Clin Chem 26 (1980): 163-8
  • Bagnarello AG, Lewis LA, McHenry MC, Weinstein AJ, Naito HK, McCullough AJ, Lederman RJ, Gavan TL "Unusual serum lipoprotein abnormality induced by the vehicle of miconazole." N Engl J Med 296 (1977): 497-9
  • "Product Information. Monistat (miconazole)." Ortho Pharmaceutical Corporation, Raritan, NJ.
Miconazole oral buccal

Generic Name: miconazole

Brand Name: Oravig, Monistat IV, Oravig

Synonyms: Miconazole oral (buccal), Miconazole (Oral)

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