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Propranolol and Hydrochlorothiazide and Food

Result of checking the interaction of Propranolol and Hydrochlorothiazide and Food for safety when used together.

Check result:

Propranolol and Hydrochlorothiazide <> Food

Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Consumer information for this interaction is not currently available.

Professional:

ADJUST DOSING INTERVAL: The bioavailability of propranolol may be enhanced by food.

MANAGEMENT: Patients may be instructed to take propranolol at the same time each day, preferably with or immediately following meals.

References:

Olanoff LS, Walle T, Cowart TD, et al "Food effects on propranolol systemic and oral clearance: support for a blood flow hypothesis." Clin Pharmacol Ther 40 (1986): 408-14
Byrne AJ, McNeil JJ, Harrison PM, Louis W, Tonkin AM, McLean AJ "Stable oral availability of sustained release propranolol when co-administered with hydralazine or food: evidence implicating substrate delivery rate as a determinant of presystemic drug interactions." Br J Clin Pharmacol 17 (1984): s45-50

Propranolol and Hydrochlorothiazide

Generic Name: hydrochlorothiazide / propranolol

Brand Name: Inderide, Inderide LA

Synonyms: Hydrochlorothiazide and propranolol

What is Propranolol and Hydrochlorothiazide?