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Ribavirin and Food

Result of checking the interaction of Ribavirin and Food for safety when used together.

Check result:
Ribavirin <> Food
Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Food can enhance the levels of ribavirin in your body. Ribavirin should be taken with food or just after eating. This will make it easier for your body to absorb the medication. Do not take it on an empty stomach. Swallow the tablet or capsule whole.

Professional:

ADJUST DOSING INTERVAL: Food enhances the oral absorption and bioavailability of ribavirin. Administration of a single oral dose of ribavirin following a high-fat meal delayed absorption (Tmax was doubled) but increased the mean peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) by up to 70% compared to administration in the fasting state.

MANAGEMENT: To ensure maximal oral absorption, ribavirin should be administered with or immediately after a meal.

References:
  • "Product Information. Copegus (ribavirin)." Roche Laboratories, Nutley, NJ.
  • "Product Information. Rebetol (ribavirin)." Schering-Plough Corporation, Kenilworth, NJ.
Ribavirin

Generic Name: ribavirin

Brand Name: Rebetol, RibaPak, Ribasphere, RibaTab, Virazole, Copegus, RibaPak 600, Moderiba, Moderiba 800 Dose Pack, Moderiba 1200 Dose Pack, Moderiba 1000 Dose Pack, Moderiba 600 Dose Pack

Synonyms: Ribavirin (Oral Inhalation)

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