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Rilutek and Caffeine

Result of checking the interaction of Rilutek and Caffeine for safety when used together.

Check result:

Rilutek <> Caffeine

Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Caffeine may increase the serum concentration of riluzole. Riluzole is metabolized by the CYP450 1A2 isoenzyme. Caffeine inhibits this particular isoenzyme. The clinical significance of this interaction is not known. The patient should be closely monitored for altered clinical effect.

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