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Skelid and Food

Result of checking the interaction of Skelid and Food for safety when used together.

Check result:

Skelid <> Food

Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Food significantly decreases the levels of tiludronate. Tiludronate should be administered on an empty stomach with 6 to 8 ounces of plain water at least 2 hours before or 2 hours after food. This will make it easier for your body to absorb the medication.

Professional:

ADJUST DOSING INTERVAL: Food significantly decreases the bioavailability of tiludronate. The manufacturer reports up to a 90% decrease in bioavailability when administered with or 2 hours after a standard breakfast. Clinical efficacy, however, was demonstrated when tiludronate was taken 2 hours before or after meals.

MANAGEMENT: Tiludronate should be administered with 6 to 8 ounces of plain water at least 2 hours before or 2 hours after food.

References: