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Sofosbuvir, velpatasvir, and voxilaprevir and Food

Result of checking the interaction of Sofosbuvir, velpatasvir, and voxilaprevir and Food for safety when used together.

Check result:
Sofosbuvir, velpatasvir, and voxilaprevir <> Food
Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Consumer information for this interaction is not currently available.

Professional:

ADJUST DOSING INTERVAL: Administration with food enhances the oral bioavailability of sofosbuvir, velpatasvir, and voxilaprevir. Relative to fasting conditions, mean sofosbuvir systemic exposure (AUC) increased by 64% to 144%, mean velpatasvir AUC increased by 40% to 166%, and mean voxilaprevir AUC increased by 112% to 435% when the combined sofosbuvir/velpatasvir/voxilaprevir formulation is administered with food.

MANAGEMENT: Sofosbuvir/velpatasvir/voxilaprevir should be administered with food.

References:
  • "Product Information. Vosevi (sofosbuvir/velpatasvir/voxilaprevir)." Gilead Sciences, Foster City, CA.
Sofosbuvir, velpatasvir, and voxilaprevir

Generic Name: sofosbuvir / velpatasvir / voxilaprevir

Brand Name: Vosevi

Synonyms: Sofosbuvir, Velpatasvir, and Voxilaprevir

What is Sofosbuvir, velpatasvir, and voxilaprevir?
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