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Symbicort 200 Turbuhaler and Food

Result of checking the interaction of Symbicort 200 Turbuhaler and Food for safety when used together.

Check result:
Symbicort 200 Turbuhaler <> Food
Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Consumer information for this interaction is not currently available.

Professional:

GENERALLY AVOID: Grapefruit juice may increase the plasma concentrations and systemic effects of orally administered budesonide. The proposed mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruits. According to the manufacturer, the systemic exposure of oral budesonide approximately doubles after extensive intake of grapefruit juice.

MANAGEMENT: Patients receiving budesonide should avoid the regular consumption of grapefruits and grapefruit juice to prevent undue increases in plasma budesonide levels and systemic effects.

References:
  • "Product Information. Entocort (budesonide)." AstraZeneca Pharma Inc, Mississauga, ON.
Symbicort 200 Turbuhaler

Generic Name: budesonide / formoterol

Brand Name: Symbicort, Symbicort Turbuhaler, Symbicort 400/12 Turbohaler

Synonyms: Symbicort

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