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Tafenoquine (Prevention of Malaria Relapse) and Food

Result of checking the interaction of Tafenoquine (Prevention of Malaria Relapse) and Food for safety when used together.

Check result:
Tafenoquine (Prevention of Malaria Relapse) <> Food
Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Food helps with the absorption of tafenoquine into the blood stream. You should take this medication with food as directed.

Professional:

ADJUST DOSING INTERVAL: Food enhances the oral bioavailability of tafenoquine. According to the manufacturer, tafenoquine peak plasma concentration (Cmax) and systemic exposure (AUC) increased by 31% and 41%, respectively, when administered as an investigational capsule formulation with a high-calorie, high-fat meal (approximately 1000 calories; 15% protein, 25% carbohydrate, 60% fat) relative to the fasted state.

MANAGEMENT: Tafenoquine should be administered with food.

References:
  • "Product Information. Krintafel (tafenoquine)." GlaxoSmithKline, Research Triangle Park, NC.
Tafenoquine (Prevention of Malaria Relapse)

Generic Name: tafenoquine

Brand Name: Arakoda, Krintafel

Synonyms: Tafenoquine

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