Valcyte and Food
Result of checking the interaction of Valcyte and Food for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.
Consumer:Food can enhance the levels of valGANciclovir in your body. To ensure maximal oral absorption, valGANciclovir should be administered with or immediately after a meal. This will make it easier for your body to absorb the medication.
ADJUST DOSING INTERVAL: Food increases the bioavailability of ganciclovir from the prodrug, valganciclovir. In 16 HIV-positive subjects, the administration of valganciclovir 875 mg once daily with a high-fat meal containing approximately 600 calories resulted in a 30% increase in the steady-state area under the plasma concentration-time curve (AUC) and a 14% increase in the peak plasma concentration (Cmax) of ganciclovir, with no delay in the time to reach peak plasma concentration (Tmax). The mechanism is unknown.
MANAGEMENT: The manufacturer recommends that valganciclovir be taken with meals.
- "Product Information. Valcyte (valganciclovir)" Roche Laboratories, Nutley, NJ.
- Brown F, Banken L, Saywell K, Arum I "Pharmacokinetics of valganciclovir and ganciclovir following multiple oral dosages of valganciclovir in HIV- and CMV-seropositiv volunteers." Clin Pharmacokinet 37 (1999): 167-76
Valcyte - Żywność 
Valcyte - Alimento 
Valcyte - Makanan 
Valcyte - Makanan 
Valcyte - Cibo 
Valcyte - Aliment 
Valcyte - Food 
Valcyte - Comida 
Valcyte - Еда 
Valcyte - Gıda 
Valcyte - طعام 
Valcyte - 食物