Vfend I.V. and Food
Result of checking the interaction of Vfend I.V. and Food for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.
Consumer:You may experience reduced absorption of voriconazole in the presence of food. Take voriconazole on an empty stomach 1 hour before or 2 hours after a meal unless otherwise directed by your doctor. This will make it easier for your body to absorb the medication.
ADJUST DOSING INTERVAL: Food reduces the oral absorption and bioavailability of voriconazole. According to the product labeling, administration of multiple doses of voriconazole with high-fat meals decreased the mean peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) by 34% and 24%, respectively, when the drug is administered as a tablet, and by 58% and 37%, respectively, when administered as the oral suspension.
MANAGEMENT: To ensure maximal oral absorption, voriconazole tablets and oral suspension should be taken at least one hour before or after a meal.
- Wohlt PD, Zheng L, Gunderson S, Balzar SA, Johnson BD, Fish JT "Recommendations for the use of medications with continuous enteral nutrition." Am J Health Syst Pharm 66 (2009): 1438-67
- "Product Information. VFEND (voriconazole)." Pfizer U.S. Pharmaceuticals, New York, NY.
Generic Name: voriconazole
Brand Name: Vfend, Vfend
Synonyms: Voriconazole (oral/injection), Voriconazole
Vfend I.V. - Żywność 
Vfend I.V. - Alimento 
Vfend I.V. - Makanan 
Vfend I.V. - Makanan 
Vfend I.V. - Cibo 
Vfend I.V. - Aliment 
Vfend I.V. - Food 
Vfend I.V. - Comida 
Vfend I.V. - Еда 
Vfend I.V. - Gıda 
Vfend I.V. - طعام 
Vfend I.V. - 食物