Drug search by name

Warfarin and High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)

Result of checking the interaction of Warfarin and High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia) for safety when used together.

Check result:

Warfarin <> High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)

Relevance: 03.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with food or lifestyle.

Consumer:

Patients with edema, hereditary coumarin resistance, hyperlipidemia, hypothyroidism, or nephrotic syndrome may exhibit lower than expected hypoprothrombinemic response to oral anticoagulants. Thus, more frequent laboratory (PT/INR) monitoring and dosage adjustment of anticoagulant may be required based on changes in the patient's condition.

Professional:

References:

Ganeval D, Fischer AM, Barre J, et al "Pharmacokinetics of warfarin in the nephrotic syndrome and effect on vitamin K-dependent clotting factors." Clin Nephrol 25 (1986): 75-80
Rice AJ, McIntosh TJ, Fouts JR, et al "Decrease sensitivity to warfarin in patients with myxedema." Am J Med Sci 262 (1971): 211-5
Walters MB "The relationship between thyroid function and anticoagulant therapy." Am J Cardiol 11 (1963): 112-4
Stephens MA, Self TH, Lancaster D, Nash T "Hypothyroidism: effect on warfarin anticoagulation." South Med J 82 (1989): 1585-6
Demirkan K, Stephens MA, Newman KP, Self TH "Response to warfarin and other oral anticoagulants: effects of disease states." South Med J 93 (2000): 448-54; quiz 455
"Product Information. Coumadin (warfarin)." DuPont Pharmaceuticals, Wilmington, DE.

Warfarin

Generic Name: warfarin

Brand Name: Coumadin, Jantoven

Synonyms: n.a.

What is Warfarin?